The conference at mmc2025 will consisted of six parallel streams comprising 36 conference and EMAG sessions.
Session Chairs: Ioanna Mela (University of Cambridge, UK) & George Heath (University of Leeds, UK)
Wednesday 2 July 1015 - 1215 & Thursday 3 July 1015 - 1215
Atomic Force Microscopy (AFM) offers powerful, label-free visualization and mechanical characterisation of biomolecules and cellular structures under native conditions. The AFM for Biosciences sessions will explore the latest advancements in AFM applications within biological and medical research, ranging from single cell down to sub-molecular scales to uncover new structural, mechanical and dynamic insights. Additionally, we will cover correlative and computational methods that enhance interpretation and data analysis to uncover the complexities of biological systems.
Keywords: Imaging, Mechanics, Biomolecules, Cells, Data Analysis.
Audience: Life, physical and multidisciplinary sciences, data analysts




Centre of Infection and Immunity of Lille, Institut Pasteur de Lille-CNRS, France
Session Chair: Sohini Kar-Narayan (University of Cambridge, UK)
Wednesday 2 July 1415 - 1615
Advances in scanning probe microscopy have continued to provide insights into nanoscale properties of a wide class of functional materials, such as polymers, oxides and 2D materials for applications in energy, neuromorphic computing, optoelectronics and sensing, to name a few. This session is dedicated to the latest developments in AFM & SPM techniques for advanced nanoscale imaging and characterisation of novel and emerging materials.


Session Chair: Kristina Rusimova (University of Bath, UK)
Thursday 3 July 1400 - 1600
Scanning probe techniques (SPM) allow us to study molecules all the way down to the single chemical bond limit, as well as in direct interaction with other molecules in an ensemble. This session will explore the state-of-the-art in the field of molecular reaction dynamics on surfaces and explore the overlap with newer variations on SPM, including in combination with optical techniques.


Session Chair: Periklis (Laki) Pantazis (Imperial College London, UK)
Wednesday 2 July 1015 - 1215
This session highlights cutting-edge optical imaging approaches that span multiple biological scales - from single cells and organoids to intact organs and model organisms. We will explore how advanced imaging techniques reveal dynamic processes in development, tissue organisation and disease progression, with particular emphasis on cancer evolution. Presentations will showcase innovations in light microscopy that enable long-term visualisation of living systems while maintaining high spatiotemporal resolution. The session aims to foster discussion on complementary imaging strategies that bridge the gap between cellular mechanisms and organismal phenotypes.
Keywords: Live optical imaging, organoids, developmental biology, cancer imaging, intravital microscopy, light-sheet microscopy, model organisms, tissue dynamics
Audience: Developmental biologists, cancer researchers, microscopy specialists, cell biologists, and biomedical scientists interested in dynamic imaging of living systems


Session Chair: Jean-Yves Tinevez (Institut Pasteur, France)
Wednesday 2 July 1415 - 1615
Life is all about dynamics and therefore tracking of biological components over time is a key topic in biology. From motors travelling on microtubules, to single cancer cells migrating, and cells flowing to build organs, the data generated with modern live cell microscopy can reveal unique information on the dynamics of Life. The goals and applications of these studies are very varied, but for them tracking is indispensable.
This session will focus on new approaches and applications of tracking for Life Sciences. It will feature invited and short talks covering both new algorithms for tracking, and innovative applications of tracking. Speakers will present cutting-edge methodologies that enhance the accuracy and efficiency of tracking biological entities, as well as novel applications that shed light on fundamental biological processes. Topics may include advancements in machine learning for tracking, analysis tools suitable for large data, and the integration of tracking data with other biological datasets.


Session Chair: Caroline Mullenbroich (University of Glasgow, UK)
Thursday 3 July 1015 - 1215
Advances in multiphoton microscopy are continually enhancing imaging performance and versatility. This session highlights cutting-edge techniques that enhance the imaging performance in challenging bioimaging applications with new and creative approaches. Examples include techniques to improve the depth penetration in scattering media, increasing speed or enhancing sensitivity and many more. Here we explore innovative solutions driving the future of nonlinear optical microscopy and their impact on biological and biomedical research.
Keywords: Nonlinear optics, multiphoton microscopy, instrumentation, microscope design,
Audience: Researchers in life and physical sciences, multiphoton microscopy experts, imaging instrumentation specialists, and data scientists in bioimaging and microscopy


Session Chair: Leo Carlin (CRUK Scotland Institute /University of Glasgow, UK)
Thursday 3 July 1400 - 1600
To generate better understanding of the mechanisms regulating cellular behaviour we must address cells in their endogenous microenvironment. This session will focus on microscopy approaches to reveal and measure the spatiotemporal dynamics, interactions, and activity of cells in (live) tissue and intact organisms.
Keywords: Intravital, biological imaging, microenvironment, spatiotemporal, live tissue imaging
Audience: Life, physical and multidisciplinary sciences


Session Chairs: Stephen Carter (University of Glasgow, UK) & Lauren Orr (University of Glasgow, UK)
Tuesday 1 July 1030 - 1230
Electrons offer several advantages over light for imaging different scales, from cellular to atomic. Fluorescence microscopy reveals a subset of labelled proteins, whereas cryo-ET can reveal labelled proteins at least an order of magnitude higher resolution than super-resolution optical techniques. Advances in correlated cryogenic-super-resolution microscopy combined with cryo-ET now enables any fluorescence image to be complemented with a high-resolution cryo-tomogram of the same specimen. This session will showcase the latest developments in minimally disruptive, bright fluorescently-tagged proteins that hold great promise for cryo-fluorescence imaging. We will explore emerging studies that combine these labelling innovations with correlated cryogenic light and electron tomography to offer unprecedented insight into viral lifecycles and virus-cell interactions. We welcome contributions from researchers working across broader developments and applications in imaging virology-related biological phenomena across all scales.
Keywords: Tracking, fluorescent protein labelling, super-resolution microscopy, viral replication, virus-host interactions

Session Chairs: Liam Rooney (University of Glasgow, UK) & Rebecca McHugh (University of Glasgow, UK)
Tuesday 1 July 1430 - 1630
The latest advancements in microscopy and cytometry are transforming our understanding of host-pathogen interactions. This session focuses on how microbes establish and maintain infections while evading host defences and antimicrobial interventions. It will showcase innovative measurement techniques that reveal the dynamic interplay between pathogens and their host. New understandings of infection dynamics rely on the latest advancements spanning the disciplines of optical, scanning probe and electron microscopy, and see the adoption of advanced sample preparation techniques, such as optical clearing and 3D infection models, and the use of quantitative image analysis methods. This session aims to address both the microbial and immunological aspects of infection biology, using interdisciplinary approaches to understand the complexities of host-pathogen interactions across spatiotemporal scales.
Keywords: infection biology, inflammation, volumetric imaging, tissue models, infection/invasion models
Audience: Life, physical and multidisciplinary sciences. Optical, electron and scanning probe microscopists and data analysts


Session Chair: Xiangli Zhong (University of Manchester, UK)
Tuesday 1 July 1030 - 1230
Focused Ion Beam microscopy has become one of the main techniques in the physical sciences and multidisciplinary sciences in recent years thanks to the rapid development of innovative tools for sample preparation, 3D imaging and analytical spectroscopy, it has significantly enhanced our understanding from the macroscopic to the sub-nanometer level covering a range of systems from metals, ceramics, polymers, composites, and biomaterials. This session discusses recent advances in characterisation and sample preparation techniques not limited to ion or electrons beams, but also conventional methods in physical and multidisciplinary sciences, ranging from (not limited to) polishing, etching/coating to imaging techniques, for all type of microscopes, examples of the related techniques are serial-section EM/FIB, TEM/STEM imaging, in-situ EM, Electron and FIB imaging, micro CT, and tomography etc.
Keywords: Focused Ion Beam, Sample preparation, 3D imaging, Electron Microscopy, Materials, Imaging
Audience: Material, physical, and multidisciplinary sciences


Session Chair: Michael Grange (Rosalind Franklin Institute, UK)
Tuesday 1 July 1430 - 1630
The use of focused ion beams (FIB) has become central in the life sciences in recent years thanks to the rapid development of innovative hardware and method developments enabling complex sample shaping, etching, welding, 3D imaging and analytical spectroscopy approaches. It has significantly improved our ability to understand intracellular complexity, with applications to volume electron microscopy and structural biology covering a range of systems from biological materials, including tissues and cells.
This session discusses recent advances in characterisation and sample preparation techniques where the use of FIB is central to understanding biology. The session is not limited to ion or electrons beams, but will also discuss methods central to FIB applications, including sample preparation (fixation/vitrification), (cryo-)ultramicrotomy, serial-section EM/FIB, Electron Tomography, SBEM imaging, micro-CT, and array tomography.
This session aims to discuss frontier of FIB developments in biology, at room temperature and at cryo, from applications to hardware.
Keywords: Focused Ion Beam, Sample preparation, Tomography, Electron Microscopy, Biological sciences, Tissues and cells
Audience: Biological and multidisciplinary sciences


Session Chair: Richard Kasprowicz (GSK plc, UK)
Thursday 3 July 1400 - 1600
The use of imaging is pervasive within drug discovery, from high content screens for profiling tens-of-thousands of perturbagens in early discovery to the use of clinical imaging techniques to support monitoring and safety decisions post candidate selection. The vast information content that can be extracted from images, paired with low cost of data generation, is today bolstered by inferences that can be made from integration with ever-more sophisticated AI/ML analytics; such factors have driven the increasing adoption of imaging to provide decision-making data making at key discovery milestones. This session focusses on innovative approaches adopted in bioimaging in industry, highlighting how data from imaging technologies drives medicine development. The session will also highlight areas where industry and academia can collaborate for adoption of novel and innovative imaging solutions.
Keywords: High content imaging, Screening, Drug Discovery, Clinical Imaging
Audience: Pharmaceutical Industry, Contract Research, Academic, Life Scientists, Data Scientists.


Session Chair: Andy Brown (University of Leeds, UK)
Thursday 3 July 1015 - 1215
This session will cover the use and value of all types of microscopy for industrial applications from manufacturing quality control, failure analysis and metrology through to product innovation. The session aims to highlight developments for microscopy in the materials industries including where collaboration between industry and academia can be useful. Topics will range from machine learning and data analysis of microscopy that supports measurement in manufacturing to advanced electron microscopy techniques for development of materials and processes that will help enable the UK energy transition.
Keywords: Metrology, Manufacturing, Product Development and Innovation, Optical and Electron Microscopy
Audience: Materials and Manufacturing Industry, Contract Research, Academic, Materials Scientists, Data Scientists


Session Chair: Sean Collins (University of Leeds, UK)
Wednesday 2 July 1015 - 1215
The energy transition requires significant advances in nano- to atomic-scale structure-function principles for accelerated development of batteries and photovoltaics to electrolysers and fuel cells and many other energy conversion and storage approaches. These technologies depend on the integration of multiple materials components, and microscopic analysis is therefore central to boosting the efficiencies of existing materials and leading on materials discovery. Across these diverse materials, efficiency gains depend on quantitative, microscopic investigation of charge carrier transport physics as well as of the materials chemistry determined by variations in atomic structure, composition, and electronic structure throughout the materials microstructure and across interfaces. A common set of microscopy challenges draws these diverse materials together, notably the combined analysis of inorganic and organic fractions and high and low atomic number constituents. This session focuses on advances in all areas of microscopy (visible light, X-ray, scanning probe, ion microscopy, SEM, and TEM) for materials for energy applications, including inorganic, hybrid, and organic semiconductors, cathode/anode and binder materials, membranes and electrolytes, and related materials.


Session Chairs: Philip Hobson (The Francis Crick Institute, UK) and Morag Rose Hunter (AstraZeneca, UK)
Tuesday 1 July 1430 - 1630
Image sets allow us to extract rich “high dimensional” datasets, with a large number of features. This has become increasingly accessible with recent developments of hardware and image analysis software. The complexity of the data has led to an explosion of machine learning- and artificial intelligence-based analysis approaches. We can now identify and differentiate complex, rare, and heterogeneous phenotypes with spatial resolution. This is useful for investigating basic biology, early to late drug discovery, and clinical applications.


Session Chair: David Scurr (University of Nottingham, UK)
Tuesday 1 July 1430 - 1630
Advances in secondary ion mass spectrometry (SIMS) have yielded significant improvements in spatial resolving power, molecular specificity and complexity of their associated imaging data-sets. These hyperspectral mass spectrometry imaging (MSI) data-sets are enabling new insights into a multidisciplinary range of academic and applied research areas from developing energy materials to novel understandings in cancer tumour heterogeneity. The increased complexity of these data-sets has been accompanied by the development of novel approaches to fully exploit the information content and the introduction of correlative workflows with other imaging techniques.


Session Chair: Sergio Bertazzo (University College London, UK)
Tuesday 1 July 1030 - 1230
Contemporary advances in microscopy and computational methods have greatly enhanced our understanding of the fundamental building blocks of living organisms. Today, it is possible to obtain the 3D structure of proteins and to see how they interact with specific chemical compounds. However, visualising interactions between compounds in vivo remain one of the key research challenges in life sciences. This session will discuss new imaging methods and techniques that are helping us to better understand in vivo systems by freezing compounds in place (cryo methods) or by directly imaging biological systems.
Keywords: Cryo microscopy, in-situ microscopy, Biology, Medicine, Chemistry, Material Sciences, Imaging.
Audience: Researchers in physics, chemistry, material sciences and life sciences, cryo and in-situ microscopists.


Session Chair: Chris Parmenter (University of Nottingham, UK)
Thursday 3 July 1015 - 1215
Electron Microscopy (EM) conducted at cryogenic temperatures has been a feature of life sciences research for over forty years. Both scanning and transmission electron microscopes play a part in understanding structures and organisation in life science samples.
An inherent challenge in this field is that such samples often contain a high degree of water, which must be stablilised before entering the vacuum of most EM’s. Prior to observation in the TEM or SEM, correct sample preparation is key to preservation of structures in as close to native state as possible. Reproducibility and challenges of sample handling such as contamination are among the biggest challenges in cryo-EM.
This session will explore the improvements in sample preparation, overcoming cryo’s biggest challenges and the resulting science unlocked by SEM and TEM.
Keywords: Cryo-SEM, Cryo-TEM, Sample preparation, contamination, soft-matter
Audience: Life-sciences, Soft-matter, Biological / Biomedical Sciences


Session Chair: Ruslan Hlushchuk (Universität Bern, Switzerland)
Wednesday 2 July 1415 - 1615
Both microCT and volume EM are three-dimensional imaging techniques that have delivered new insights into biological systems in recent years. Volume EM encompasses imaging technologies based on both transmission and scanning electron microscopy enabling revealing of the 3D ultrastructure of the cells and tissue. MicroCT provides lower resolution in comparison to volume EM but is non-destructive and can therefore be combined ex vivo with other methods including volume EM.
This session is aimed to address recent advances in volume EM and ex vivo applications of microCT in preclinical and biomedical research (with or without contrasting agents or dyes), including correlative imaging using one of these approaches or both.
Keywords: ex vivo microCT, contrast-enhanced microCT, volume EM, correlative imaging, three-dimensional imaging

EMPA Swiss Federal Laboratories for Materials Science & Technology, Switzerland

Session Chairs: Kurt Anderson (The Francis Crick Institute, UK) and Martin Jones (The Francis Crick Institute, UK)
Thursday 3 July 1400 - 1600
Image data can be used to inform a wide variety of quantitative models. Models can be used to inform the image acquisition process itself or to study physical and biological samples across multiple scales. The development and testing of models necessarily relies on the use of advanced image analysis methods to derive quantitative data from micrographs. This session will explore the interplay between imaging and the development of associated quantitative models.


Session Chair: John Wheeler (University of Liverpool, UK)
Wednesday 2 July 1015 - 1215
EBSD is a fundamental tool for describing microstructures in crystalline materials, to understand better the processes that form them and how properties such as cost and reliability may be improved. It has often been applied to alloys of relatively restricted crystal symmetry (cubic and hexagonal) but in recent years has been extended to a greater variety of materials such as perovskites, high entropy alloys, shape memory alloys, light emitting diodes etc. some of which have lower symmetries (tetragonal, orthorhombic). In parallel, geologists have been investigating a wide range of minerals with different symmetries. In this session we invite contributions that illustrate the uses of EBSD on novel manufactured crystalline materials and on minerals, seeking emerging themes and challenges.
Keywords: EBSD, Alloy, Mineral, Crystalline material
Audience: metallurgists, ceramicists, geologists


Session Chair: Nathalie Gey (CNRS - Université de Lorraine, France)
Wednesday 2 July 1415 - 1615
Electron Backscatter Diffraction (EBSD) is a scanning electron microscope (SEM) based technique that gives the local crystal orientation in a sample. The progress made over the years has significantly improved the quality in the orientation determination while reducing the data acquisition time. So that today, EBSD is a powerful tool for enriched microstructure characterization from the millimeter to the nanometer scale.
The session will focus on the recent advances in the EBSD and related techniques, such as transmission Kikuchi diffraction (TKD), electron channelling contrast imaging (ECCI), 3D Orientation Imaging and could also question how machine learning could further assist future progress. The session will include state-of-the-art developments in new generation of detectors, in Kikuchi Pattern analysis for advanced material data extraction and in the latest data post-processing routes. Coupling EBSD with other techniques such as in-situ deformation and temperature tests, nanoindentation and Raman experiments will also be in the scope of the session.
Keywords: Electron Microscopy, Orientation, Diffraction, Materials, Imaging
Audience: Researchers in physics, materials science and geology, electron microscopy experts and data analysts


Session Chair: Liz Duke (EMBL Hamburg, Germany)
Thursday 3 July 1015 - 1215
In recent years the usage of X-ray techniques, and particularly X-ray imaging, in biology has seen a significant increase. This is in part due to advances laboratory X-ray source technology but also due to exploitation of synchrotron facilities by biologists. In this session we will highlight the power of X-rays with their ability to probe deep into soft matter such as tissues and cells; where the results obtained using X-rays are at the heart of the work being presented, either standing alone or shoulder to shoulder alongside other techniques in order to provide answers to the biological question posed.
Keywords: X-rays, Imaging, Tissue, Cells
Audience: Those actively involved in using X-rays in their biological research and those interested in finding out what is possible with X-rays.


Session Chair: Silvia Cipiccia (University College London, UK)
Thursday 3 July 1400 - 1600
Computation imaging techniques including ptychography, holography and coherent diffraction imaging, have revolutionised the way in which microscopy is performed at the nanoscale. By replacing the lens with a computational algorithm, these techniques have overcome the limitations of conventional microscopy due to lens aberrations. This session aims to bring together researchers working on technique and algorithm development, as well as applications in the X-ray regime, from life science, to energy material and magnetic domains studies.
Keywords: Ptychography, X-ray, Computational Imaging, Coherent Diffraction Imaging, Holography
Audience: Those actively involved in nanoscale x-ray imaging technique and applications as well as anyone curious about nanoscale imaging and interested in knowing more


Session Chairs: Gail McConnell (University of Strathclyde, UK) & Myfanwy Adams (John Innes Centre, UK)
Tuesday 1 July 1030 - 1230
Late breaking submissions are invited to report the very latest results in microscopy. This abstract deadline is not intended to be merely an extension of the general submission deadline: instead this session provides an opportunity for researchers to present the most exciting recent developments in the field.
You can view the EMAG session keywords on the EMAG 2023 webpage, the mmc2023 conference sessions are listed below.

University of Regina, Canada
Talk title: Inside and out: Functional cellular assays using correlative AFM-confocal
Born and raised in Guelph, Ontario, Tanya studied Biology and Chemistry at the University of Waterloo (BSc Co-op 1990), Biophysics (PhD 1996) as a Natural Science and Engineering Research Council (NSERC) scholar at Ottawa University and the National Research Council (NRC), X-ray crystallography at Purdue University as a NSERC postdoctoral fellow, and advanced microscopy at NRC as a NSERC visiting fellow. Starting at the University of Regina (UofR, 1999), Tanya launched the atomic force microscopy (AFM) facility and pioneered techniques to study mechanisms of polarized and non-polarized growth in live fungal and moss cells by AFM. As a Full Professor, her group has studied a variety of mechanisms related to opportunistic fungal pathogens, pathogenic and mutualistic bacteria. The group uses a battery of microscopy techniques including AFM, fluorescence, confocal, transmission and scanning electron microscopy, and near-field interferomic infrared AFM (ALS, Berkeley) to complement traditional and modern (metabolomics, proteomics) biochemical approaches.
Of special interest to the group is how xenobiotics, such as herbicides and antifungals, impact nontarget (microbes, human cells) and target (opportunistic pathogens) organisms, respectively. Their correlative AFM-confocal microscopy assays result in multiplexed “cellulomic” response data that they can use to address these environmental and therapeutic health questions. Tanya’s research is supported by NSERC, Canada Foundation for Innovation and the Saskatchewan Health Research Foundation, and her various awards include a visiting fellowship to the National Institutes of Health, an AstraZeneca Research Award, Canadian Cancer Society Award and the YWCA Woman of Distinction Award.

Weizmann Institute, Israel
Talk title: High-speed atomic force microscopy captures rare and dynamic protein events
Shifra holds a BSc (summa cum laude) and PhD in chemistry from the Hebrew University in Jerusalem (Israel). During her PhD, conducted under the guidance of Prof. Gil Shoham, Shifra used X-ray crystallography, small angle X-ray scattering (SAXS), and molecular dynamics simulations (MDS) to characterize structurally and mechanistically the proteins composing the hemicellulose utilization systems of thermophilic bacteria.
After her PhD, Shifra went to learn the pioneering technique of high-speed atomic force microscopy (HS-AFM) from the lab of Prof. Simon Scheuring (Cornell University, USA), one of a handful of groups worldwide who use HS-AFM to study the structure and dynamics of proteins. Using HS-AFM and single-particle cryo-electron microscopy (cryo-EM), Shifra discovered a rare and reversible structural state for the TRPV3 ion channel, with potential far-reaching biological implications, laying the foundation for many new directions in ion channel research.
In June 2024, Shifra opened her own independent research group at the Department of Chemical and Structural Biology at the Weizmann Institute, where she combines use of HS-AFM and cryo-EM to study the structure, dynamics, and function of diverse membrane protein systems. Shifra is the recipient of many awards and fellowships, including the prestigious Azrieli PhD fellowship, the Rothschild and Zuckerman postdoc fellowships, and most recently, the Alon fellowship for outstanding young faculty members.

Institute of Structural Biology of Grenoble, France
Talk title: AFM topography and integrated structural biology
Jean-Luc Pellequer received his Ph.D. in Molecular Biology from the Université Louis Pasteur, Strasbourg, in 1993. After a postdoctoral fellowship in Biochemistry and Molecular Biophysics at Columbia University (Barry Honig), he was a research associate in the Department of Molecular Biology at the Scripps Research Institute in La Jolla (Elisabeth Getzoff and John Tainer).
Jean-Luc developed a new method for predicting protein epitopes based on the sequence propensity in protein secondary structures. He then developed skills in comparative protein modeling to understand protein function, with a particular interest in coagulation factors. This expertise led him to participate in the early CASP activities (~2000). In 2001, he joined the Atomic Energy and Alternative Energies Commission (CEA) in Marcoule (near Avignon) to develop his independent research group in structural bioinformatics.
In 2007, Jean-Luc Pellequer created the Laboratory of Interactions and Molecular Recognition (LIRM) and actively participated in the development of atomic force microscopy imaging of isolated single molecules and integrated structural biology using AFM topography. In 2015, Jean-Luc decided to join the Institute of Structural Biology of Grenoble and heads the AFM team in the Methods and Electron Microscopy group to further develop software in AFM image processing, force spectroscopy, and nanobiomechanics. Jean-Luc is the co-founder of the AFMBioMed conferences and summer schools (afmbiomed.org). He acts as the current president of the International AFMBioMed Conference Association.

Centre of Infection and Immunity of Lille, Institut Pasteur de Lille-CNRS, France
Talk title: Recent technological advances: correlative light-atomic force-electron microscopy and AFM-based automation
Frank Lafont received his Ph.D in Molecular and Cellular Pharmacology in 1993 from University P&M Curie, Paris with practical work at the Ecole Normale Supérieure, Paris (Pr A Prochiantz). From 1993 to 2000 he was postdoctoral fellow at the EMBL, Heidelberg in Cell Biology (Pr K Simons). In 2000 he was appointed as Junior Lecturer at the Univ of Geneva in the Biochemistry Fac. and at then at the Univ. Med. Center (Pr FG van der Goot) before joining in 2004 the EPFL, Lausanne, Switzerland as Staff Scientist in the Brain & Mind Inst. (Pr S Catsicas). Since 2005, he is CNRS Group Leader at the Institut Pasteur Lille.
Frank Lafont made several key contributions in membrane trafficking of cellular polarity and in host-pathogens interactions especially through membrane microdomains and involving the autophagic cell response. Noteworthily, his group has shown how several bacteria and viruses hijack the autophagy pathway for successful invasion. Being interested in the physical properties of membranes engaged in interactions with pathogens, while at EPFL working with S Casas, he decided to use Atomic Force Microscopy (AFM) to characterize elastic (membrane) domains within living cells.
In 2005, Frank Lafont launched his group on Cellular Microbiology and Physics of Infection at the Institut Pasteur de Lille, participating in the creation of the Center of Infection and Immunity of Lille in 2010 that he will be the Director of in 2026. There, he could validate the Stiffness Tomography method initiated in Lausanne to discriminate between intracellular compartments of different elastic properties. He established, for the first time, the correlative measurement of a unique biological sample using the three types of microscopy: photonic, electronic and near-field. He pioneered the automation using AFM with the aim of middle throughput screening based on biophysical parameters such as Young modulus. His multidisciplinary group gathering Health, Biology and Physics expertise is deeply involved in the elastic analysis of living matter at several scales from individual molecules to cells and tissues.

University of Cambridge, UK
Talk title: SPEM: Scanning Plasmon-Enhanced Microscopy for Simultaneous Optoelectrical Characterization
Dr Di Martino is an Associate Professor in Device Materials at the Department of Materials Science & Metallurgy, University of Cambridge. Her recognition on an international scale led to several awards (such as the ABTA Doctoral Researcher Award, the Physicist of the Month award from the American Physical Society, the Prestigious Winton Fellowship and the 2024 Emerging Alumni Leader Award from Imperial College London) and she has been elected both Fellow of the Institute of Physics (IoP) and Fellow of the Institute of Materials, Minerals & Mining (IOM3) in recognition for her stellar contributions to the field of both physics and materials science.
Her research develops innovative ways to use spectroscopy and light-matter interaction to investigate a wide range of cutting-edge device materials, from novel semiconductor and dielectric interfaces to magnetic and superconductive thin films, by which applications such as low power electronics, high performance memory devices and neuromorphic computing can directly benefit. She develops ultra-concentration of light trapped inside nanocavities into an innovative fast methodology for studying real-time movement of individual atoms that underpins new generation of devices. To date, she has raised research funding from diverse national and international sources, including the European Research Council.

University of Limerick, Ireland
Talk title: The hunt for sustainable piezoelectric crystals using multiscale characterisation
Dr Sarah Guerin, Associate Professor in Sustainable Energy Harvesting, graduated with a BSc in Applied Physics, going on to complete her PhD in piezoelectric modelling with Prof Damien Thompson. After receiving her PhD in 2018, her postdoctoral research was carried out in the modelling theme of SSPC, the Science Foundation Ireland Research Centre for Pharmaceuticals, in which she is now a funded investigator. She now runs her research group, the Actuate Lab in the Department of Chemical Sciences and Bernal Institute in the University of Limerick, Ireland. She has been awarded over €2.5M to work on both in-silico and ex-silico engineering of biomolecular crystals, primarily for application areas in eco-friendly sensing and pharmaceuticals. She currently works with a large number of international research groups as a leader in computationally predicting the electromechanical properties of novel molecular crystals. She has been awarded the British Association of Crystal Growth Young Scientist of the Year Award and is the 2023 Research Ireland Early Career Researcher of the Year.

University of Nottingham, UK
Talk title: On-surface chemistry: "It's not the destination, it's the journey"
Alex Saywell is a Royal Society University Research Fellow and holds a proleptic lectureship at the University of Nottingham. He has led a research group since 2016, focusing on the highly interdisciplinary area of molecular reactions and interactions on surfaces. His research employs scanning probe microscopies (SPM), including scanning tunnelling microscopy (STM) and atomic force microscopy (AFM), to characterise the structure and properties of complex functional molecules at surfaces in ultra-high vacuum (UHV) environments.
A particular focus is the characterisation of on-surface synthesised 1D and 2D molecular structures and the development of methodologies for producing specific reaction products. SPM techniques provide real space images of molecule/substrate systems either as static structures or as dynamic processes and can provide a wealth of insight into the evolution of on-surface reactions. In addition to this global picture of the molecule/substrate system, the STM/AFM probe may be used to investigate the chemical, conformational, and electronic properties of individual molecules or specific chemical groups within a molecule. Knowledge and understanding of such interactions will facilitate the development of new functional materials whose attributes are determined by their nanoscale properties. In addition to SPM of molecule-substrate systems, various complementary experimental techniques are employed within his research, including synchrotron based XPS, NEXAFS and XSW.

Institute of Physics of the Czech Academy of Science, Czech Republic
Talk title: Accessing the photophysics of single chromophores and clusters with scanning probe
Martin Svec obtained his MSc. and PhD. degrees at Faculty of Mathematics and Physics of the Charles University in Prague. His thesis, dedicated to metal adsorption on semiconductors, was performed at the Institute of Physics of the Czech Academy of Sciences, in the Laboratory of Scanning Tunnelling Microscopy. Between 2009-2011 he worked as a post-doc in Madrid at the Center of Astrobiology of the Spanish National Research Council, investigating 2D materials and artificial pathways of prebiotic synthesis. After returning to Prague and taking the senior role in the STM/AFM laboratories in the group of Dr. Jelinek, got the Otto Wichterle Award for young researchers. In 2019 he established in the labs the research line of the scanning probe microscopy with light, fully focussing on photophysics of molecules at nanoscale and became a PI in a series of national projects. Currently he is building a new laboratory at the Institute of Organic Chemistry and Biochemistry in Prague, aimed at the single-molecule investigation with emphasis on their photonic properties, combining tip-enhanced luminescence and ultrahigh-resolution imaging with AFM and STM. During his career, he co-authored more than 60 articles in peer-reviewed journals, gaining an h-index of 24 with over 2000 citations. At present, he is an acting member of the evaluation committee of the Czech Science Foundation at the Condensed Matter Physics panel and regularly provides peer-reviews on scientific manuscripts in high-ranking journals.

University of Oxford and Ludwig Cancer Research, UK
Talk title: Imaging cell to cell communication in zebrafish
The White lab is interested in the intersection between developmental biology and cancer biology. There are many parallels in these processes, including both cell-intrinsic fate decisions as well as cell-cell interactions in the microenvironment. Using both zebrafish and human pluripotent stem cell models of melanoma, his lab has described a mechanism called “oncogenic competence” that explains why DNA mutations are only sometimes able to initiate tumors. His lab has found that the ability to initiate melanoma is strongly influence by the anatomic position of the cell along the body axis. Whereas cutaneous melanomas are enriched for BRAF mutations, acral melanomas more commonly harbor amplifications of genes such as CRKL. These specific oncogenes depend upon the positional gene program in the melanocytes, suggesting that an anatomic code could be a targetable vulnerability in melanoma. Finally, his work has more recently investigated how cells in the TME such as keratinocytes and adipocytes promote melanoma progression and metastasis, acting through signaling and epigenetic mechanisms. He has been awarded the NIH Director’s New Innovator Award, as well as awards from the Melanoma Research Alliance, the Pershing Square Foundation Award, the American Cancer Society, and the Mark Foundation ASPIRE award.

University of Manchester, UK
Talk title: Cellular mechanisms directing neuronal differentiation during vertebrate development
Raman Das performed his PhD research with Marysia Placzek and Stuart Wilson at the University of Sheffield followed by postdoctoral training with Kate Storey at the University of Dundee. He then established his research group at the University of Manchester which focuses on investigating the cellular behaviour directing neuronal differentiation in the developing vertebrate embryo. This research takes advantage of innovative long-term live-tissue imaging techniques to uncover the mechanisms through which differentiating neurons dynamically reinterpret signalling cues through molecular remodelling of the primary cilium to ultimately polarise and initiate a nascent axon in the correct orientation.

Turing Centre for Living Systems, France
Talk title: Comprehensive Visualization and Analysis of Cell Lineage Trees
Léo did his undergraduate studies in Theoretical Computer Science at the University of Bordeaux, France. He then moved to Montpellier in October 2011 to pursue a doctorate at the interface between Computer Science and Developmental Biology. Supervised by C. Godin and P. Lemaire, he looked at the stereotypical development of ascidian embryos. He developed algorithms to reconstruct and track cell shapes across time from 3D movies of fluorescence acquired using light-sheet microscopy. He used these reconstructions to model cell-cell communications and showed that in ascidians, these communications are mediated, at least partially, by contact-area between cells.
After his Ph.D, in January 2016, Léo moved to Virginia, USA, in the group of Philipp Keller at Janelia Research Campus. There, he developed algorithms to detect and track cell positions over extensive periods of time during mouse embryogenesis. Using these reconstructions, he built the first cell fates and morphodynamic atlas of mouse embryonic development post implantation. The construction of this atlas was made possible by TARDIS, the algorithm he developed to co-register multiple embryos temporally and spatially.
Then in 2019, after an 8-month sabbatical backpacking around the world, he went to Berlin, Germany, to join the group of Dagmar Kainmueller where he started his work on Drosophila development.

University of Toulouse, France
Talk title: Development of a pipeline and tools for 4-dimensional tracking and stereotyping of large imaging datas
Julie Batut, CNRS Research Director, Head of the Multimodal Modelling of Organ Development team, CBI MCD, Toulouse, Coordinator of the Femmes & Sciences CBI PhD Programme mentoring programme.
Julie Batut joined the CNRS in 2008 as a researcher in Developmental Biology. Since 2023, she has led a multidisciplinary research team at the Toulouse Centre for Integrative Biology, using mathematical modelling, zebrafish embryo, imaging and data learning to understand organ formation.
She is a research director at the CNRS, an embryologist and expert in neurogenesis and the acquisition of cell shape during embryonic development. She is developing a multidisciplinary collaborative project (mathematics, computer science, image analysis & engineering to understand living organisms). Her project focuses on understanding the mechanisms involved in organ formation. It is particularly interested in the olfactory sensory organ in the zebrafish embryo.
She is deeply committed to developing and transmitting inclusive, multidisciplinary science.
Links : https://cbi-toulouse.fr/fr/equipe-batut https://www.femmesetsciences.fr/mentorat

Cornell University, USA
Talk title: Pushing the limits of multiphoton imaging in living systems
Chris Xu is the IBM Chair Professor of Engineering at Cornell University. He is the Director of the School of Applied and Engineering Physics and the Mong Family Foundation co-director of Cornell Neurotech. His current research areas are multiphoton microscopy for deep and fast imaging and fiber-based devices and systems for optical imaging. Prior to Cornell, he was a member of technical staff at Bell Laboratories and pioneered breakthrough development of fiber optic communication systems based on differential phase-shift keying. He received his Ph.D. in Applied Physics from Cornell University and his B.S. in Physics from Fudan University. He has won the NSF CAREER award, Bell Labs team research award, the Tau Beta Pi Professor of the Year Award, and two teaching excellence awards from Cornell Engineering College. He received the 2017 Cornell Engineering Research Excellence Award. He is a fellow of the Optica and a fellow of the National Academy of Inventors.

INSERM, France
Talk title: Scanless two-photon voltage imaging
Ruth completed her PhD at the Cambridge Advanced Imaging Centre under the supervision of Dr Kevin O'Holleran, where she worked on super resolution light field microscopy amongst other projects. She moved to Paris for her postdoctoral research, to work in the team of Valentina Emiliani at the Vision Institute. Her postdoctoral research has been focused on the development of advanced optical approaches to manipulate brain function (in other words, to read and write neural activity). She also spent six months as a visiting research scientist at Janelia Research Campus working on programmable microscopy for whole brain imaging in zebrafish.

Cancer Research UK Scotland Institute, UK
Talk title: 4D regulation of myeloid cells in cancer
Leo Carlin leads the Leukocyte Dynamics cancer immunology group and the Beatson Advanced Imaging Resource (BAIR) advanced microscopy team at the Cancer Research UK Scotland Institute (CRUK SI) in Glasgow. The Leukocyte Dynamics Group aim to uncover how immune cells, in particular, the myeloid cells of the innate immune system, can exert both pro- and anti- tumour activity and how this can be understood and/or manipulated for better patient treatment strategies. The BAIR team provides a comprehensive pipeline of advanced microscopy support and intellectual input to address questions from the broad research community we are fortunate to interact with. Leo did his BSc in Immunology at UCL followed by a PhD imaging immune cells at Imperial. He used his enthusiasm for microscopy to address the function of first NK cells, and then monocytes during postdoctoral training at KCL. He started the Leukocyte Dynamics Group at Imperial in 2013 and moved to the CRUK SI (then called the Beatson Institute) in 2016.

University of Würzburg, Germany
Talk title: Translational super-resolution microscopy of peripheral neuropathies
Katrin Heinze leads the Molecular Microscopy Group at the University of Würzburg, Germany, and develops advanced imaging pipelines and analysis tools to visualize biological processes in cells and tissues. Trained as a physicist and life scientist, her research encompasses fluorescence techniques ranging from the molecular to the whole-organ scale.
After completing her PhD in 2002 under the mentorship of Petra Schwille, she was awarded the Otto Hahn Medal for her thesis work. She then joined Paul Wiseman’s lab at McGill University in Montreal as a Max Planck Fellow, where she honed her expertise in cutting-edge imaging techniques. In 2006, she transitioned to lead the Department of Optical Engineering at the Institute of Molecular Pathology in Vienna, Austria. Building on this experience, she established her own lab at the University of Würzburg in 2011 as a junior group leader, advancing to the rank of full professor in 2020.
Katrin Heinze is passionate about fostering interdisciplinary collaborations, striving to bridge the gap between fundamental research and clinical applications. Currently, she is the elected spokesperson of the Rudolf Virchow Center for Integrative and Translational Bioimaging. Her work continues to shape the fields of microscopy and translational bioimaging, contributing to breakthroughs in understanding complex biological systems and improving approaches to personalized medicine.

Centre for Structural Systems Biology, Germany
Talk title: Developing cryo super-resolution fluorescence microscopy for the correlation with cryo-ET
Rainer Kaufmann gained his PhD in Physics from the University of Heidelberg developing single molecule based super-resolution fluorescence microscopy. Afterwards he spent 6 years as a postdoc at the University of Oxford, with a focus on combining super-resolution fluorescence microscopy with electron microscopy. He is one of the pioneers in the field of cryo super-resolution fluorescence microscopy. Since 2017, he is a PI at the Centre for Structural Systems Biology (CSSB) in Hamburg and the Department of Physics at the University of Hamburg.

University of Tübingen, Germany
Talk title: Collective elimination of bacterially-infected host cells is driven by mechanical cell competition coordinated via ERK activation waves
Lara Hundsdorfer is a PhD candidate in the Bastounis lab at the
University of Tübingen (Germany) specialising in cell biomechanics and
host-pathogen interactions. Her research explores how mechanical
stretch impacts the behavior and infection of epithelial cell
monolayers. To investigate this, she employs interdisciplinary
approaches, that include live-cell microscopy, computational analysis,
bioengineering, cell biology, and microbiology. Before starting the
PhD, she studied technical biology (B.Sc. & M.Sc.) at the University
of Stuttgart (Germany). The studies included biological training in
theory and in the laboratory, and she focused on computational
modeling of biological processes. During her studies, Lara gained
hands-on experience through internships at ProImmune Ltd (Oxford, UK) and CureVac (Tübingen, Germany), where she deepened her understanding of the field.

ADA Forsyth Institute in Cambridge, Massachusetts, USA
Talk title: Bacterial High-Rises in Your Mouth: What Structure Tells Us About Microbial Community Function
Jessica Mark Welch is a Senior Scientist at the ADA Forsyth Institute in Cambridge, Massachusetts, USA. She received her B.A. and Ph.D. in biology from Harvard University and worked for much of her career at the Marine Biological Laboratory in Woods Hole, Massachusetts, before joining the ADA Forsyth Institute in 2022. The goal of her research group is to understand the structure and function of bacterial communities in the mouth and to learn how the members of the microbial community interact, how they impact human health, and potentially, how the properties of the community can be manipulated to benefit human health.
Dr. Mark Welch and her team use both imaging and DNA sequencing approaches to investigate the structure and organization of the oral microbiome. She is co-developer of the CLASI-FISH method to use combinatorial labeling and hyperspectral imaging microscopy to identify many types of bacterial cells simultaneously in a micrograph. Using CLASI-FISH, she and her colleagues have discovered highly organized, complex structures in human dental plaque, on the human tongue, and in environments as diverse as the mouse colon and the surface of kelp and other marine algae. Her group uses DNA sequence data to construct pangenomes and examines metagenomic data to investigate why different bacteria live where they do, and how we can encourage the growth of health-promoting bacteria in the mouth.
Dr. Mark Welch curates the Human Oral Microbiome Database to provide the research community with high-quality, curated information about oral bacteria, their genomes, and their distribution throughout the mouth. More than two-thirds of oral bacterial species can be cultivated, but some are still “uncultivable” and Dr. Mark Welch and her team are working to cultivate these not-yet-cultivated bacteria and sequence their genomes to broaden and deepen the genomic information available for the oral microbiome.

University of Birmingham, UK
Talk title: Ion beam for Metallurgy
Yu-Lung Chiu is a Professor of Physical Metallurgy at the School of Metallurgy and Materials, University of Birmingham and he also leads the electron microscopy facility at the University. Yu-Lung obtained his PhD at the University of Hong Kong, and then worked at ONERA (France), EPFL and University of Auckland, before his current employment at Birmingham. Yu-Lung’s current research focuses on understanding the microstructure-performance relationship in advanced structural alloys, including those for aerospace and nuclear applications. Many of his research activities involve the applications of ion and electron beams for sample preparation and microanalysis.

Warwick University, UK
Talk title: The use of FIB and related techniques to characterise battery materials and steels
Geoff studied for a BSc, MSc and PhD in the physics department at Warwick University before moving to the Materials Department at Loughborough University. He stayed at Loughborough 12 years and had a permanent research position before leaving for WMG in 2015 to set up and run the WMG microscopy facility. Throughout his career Geoff has worked with, managed and done equipment development work on various (mostly microscope based) characterisation tools. Geoff is now an associate professor at WMG and leads the WMG microscopy area that has been specially configured for studying both battery materials and steels.

Human Technophile, Milan, Italy
Philipp S. Erdmann is a Chemical and Structural Biologist specializing in cryo-Electron Microscopy. Born in Würzburg, Germany, he began his academic journey at the Julius Maximilian University of Würzburg, focusing on Organic Chemistry.
Philipp earned his PhD from Ludwig Maximilian University of Munich, where he worked on chemical optogenetics, using light to control endogenous ionotropic glutamate receptors. After his PhD, he moved to the Massachusetts Institute of Technology for a postdoctoral fellowship, working on imaging techniques for synaptic proteins.
In 2016, Philipp joined the Max Planck Institute of Biochemistry, leading a project group in Structural Biology for 3D correlative FIB milling of autophagic structures and ribosome biogenesis.
Currently, Philipp is a Research Group Leader at Human Technopole in Milan, Italy. His research focuses on methods for subcellular protein localization and developing techniques in cryo-focused ion beam milling, cryo-lift out, and cryo-electron tomography. He addresses biological questions related to phase separation in neurodegenerative disorders, and develops protein nanostructures as tags for cryo-ET.

Frederick National Laboratory, National Cancer Institute, NIH, USA
Talk Title: FIB-SEM as a volume EM approach - insights from imaging cellular ultrastructure in 3D
Kedar Narayan is a Senior Scientist and Group Leader at the Center for Molecular Microscopy at Frederick National Laboratory and National Cancer Institute, USA. Kedar has a Ph.D. in immunology, with an emphasis on biophysics and imaging, and a background in chemistry, pathology and software engineering. His group has developed and applied FIB-SEM and other volume electron microscopy (vEM) technologies to questions in cancer and cell biology. Specific areas of Kedar’s research focus are deep learning/AI, correlative imaging, and vEM tool development; he has co-authored more than fifty papers and given invited talks around the world. His community work includes co-organizing conferences on volume EM and “large data”, leadership on data working groups, and creating common metadata standards for the field. As a leading member of the volumeEM community, Kedar is committed to the growth and democratization of the field.

GSK, UK
Talk title: Bioimaging from Cell to Organ: Enhancing Our Understanding of Drug and Target
Dr. Andy Nicholls is the Bioimaging Global Head at GSK, where he oversees the application of bioimaging solutions to drug discovery and development across all business areas. A distinguished scientist and leader, Dr. Nicholls directs strategic initiatives in imaging solutions, ranging from intracellular measurements and single-cell imaging to tissue and medical imaging of preclinical disease models.
He also chairs an internal network that aligns imaging applications globally within GSK, fostering a community of practice. He maintains a network of global academic collaborations, advancing new imaging solutions and analytics to enhance biological understanding in drug development. Before his current role, Andy spent over a decade in GSK's UK Investigative Safety operation, leading scientific studies to address critical safety issues in drug development and eventually leading the department. His early work in academia contributed to the establishment of metabolomics, helping to set standards in this emerging field. With over 55 peer-reviewed publications, he has significantly impacted the literature in metabolomics. He is a Fellow of The Royal Society of Chemistry, reflecting his contributions and leadership in the wider support of chemistry.

AstraZeneca, UK
Talk title: Driving Innovation: Machine Learning in Imaging Assays
Aditi is a Senior Research Scientist within the Cell Assay Development team in Discovery Sciences at AstraZeneca, where she has been contributing to preclinical drug discovery research for over three years. Her work focuses on leveraging her expertise in high-content imaging, machine learning, and super-resolution microscopy to accelerate automated drug discovery.
In 2020, Aditi earned her PhD in cancer biology at the Oxford Brookes University, where she explored the intricacies of cisplatin resistance and subcellular modifications through super-resolution live-cell microscopy. She further honed her imaging expertise during a postdoctoral fellowship in neurobiology, delving into the complex protein-protein interactions of acetylcholine receptor and it’s interacting partners involved in backward speech. These experiences laid a solid foundation for her multidisciplinary approach to research.
Beyond her professional achievements, Aditi is deeply passionate about the integration of technology and science, particularly in the realms of machine learning and advanced microscopy techniques. She is an advocate for collaborative innovation, constantly seeking new ways to bridge the gap between scientific inquiry and practical applications in drug discovery research.

NPL, UK
Talk title: Industry through an Objective Lens
Eleanor Merson completed an MEng degree in Materials Science and Engineering at the University of Leeds, followed by a PhD on the characterisation of titanium alloy welds which was supported by TWI. The focus of this work was the microtexture and grain boundary distribution within the welds, and as such EBSD was heavily used as a technique. Following this she briefly worked for Namtec as a technologist, before moving on to Sandvik to work in tool development for the next 9 years. While at Sandvik, Eleanor worked in various roles, including development engineer, R&D Department Manager and Composite machining Specialist. Many of the projects were around machining of composite materials – either understanding how the composite properties affected the machining process, or trying to improve the tool materials for longer tool life.
Following this, Eleanor worked as the Technical Development Manager for Lowe and Fletcher, developing new fire curtain concepts for two of the largest producers in the UK. Eleanor moved on to work on development of industrial safety barriers, first as a project manager, later as the head of testing at A-Safe, who are a large producer of polymer safety barriers.
Eleanor has been at NPL leading the Manufacturing Metrology group in Huddersfield since 2023. The group exists to help the manufacturing industry with problems related to measurement, and increasingly confidence in data in machine learning and other digital applications.

Johnson Matthey, UK
Talk title: Driving Innovation at Johnson Matthey: The Role of Microscopy in Industrial Applications
Mark completed undergraduate degree in Nanotechnology at the University of Leeds in 2014. His subsequent PhD was sponsored by AstraZeneca and delved into using electron microscopy for analysis of pharmaceuticals. Mark's work, centred on low-dose TEM with the aim to detect subtle amounts of crystallinity within amorphous solid dispersions as well as exploring novel microscopy methods to analyse these materials.
Following his PhD, Mark assumed the role of an experimental officer in TEM at Leeds funded by EPSRC and the Henry Royce Institute to analyse organic and inorganic systems. Then in 2021, he transitioned to Johnson Matthey, channelling his expertise in TEM, SEM, and FIB to characterise materials vital for hydrogen technologies, clean air and catalyst technologies, propelling advancements in sustainable energy and catalysis.

University of Cambridge, UK
Dr. Alice Merryweather is the Henry Sidgwick Research Fellow at Newnham College, University of Cambridge. She specializes in the development and application of innovative optical microscopy techniques to study dynamic processes in battery electrodes during operation.
After earning her undergraduate degree in chemistry and physics from Durham University in 2018, Alice completed an MRes in Nanoscience and Nanotechnology at the University of Cambridge in 2019. Her PhD research was conducted in Cambridge at the Cavendish Laboratory and the Yusuf Hamied Department of Chemistry, under the supervision of Prof. Akshay Rao and Prof. Dame Clare Grey. This work focused on real-time optical imaging of ion-transport dynamics in individual particles of battery electrode materials, and earned her the Cavendish Prize in Experimental Physics.
Alice’s continued research seeks to understand the fundamental challenges facing the next generation of battery materials by examining kinetic limitations and degradation mechanisms through optics-based characterisation. Her work aims to improve the understanding of reaction heterogeneity and inform the design of batteries with faster charging times and longer lifespans.
In addition to her academic achievements, Alice is co-founder of illumion, a start-up company that has commercialised her optical microscopy methodology as a benchtop scientific instrument, making the technique more readily accessibility to the battery research community.

Foshan Xianhu Laboratory, China
Talk title: Atomic-scale microstructure of lead halide perovskite thin films
Dr Mathias Uller Rothmann is a Natural Science Foundation of China Overseas Excellent Young Research Fellow at Foshan Xianhu Laboratory and has spent the last ten or so years studying photoactive perovskites with various electron microscope techniques. He obtained his M.Sc. in Physics and Nanotechnology Engineering from the Technical University of Denmark and his PhD in Materials Science and Engineering at Monash University in Melbourne, Australia, which was followed by a postdoc at the University of Oxford. He has published several papers on electron microscopy and photoactive perovskites, including papers in Science and Nature Energy, and he is currently working on further developing advanced microscopy techniques to study this class of materials and their associated devices.

University of Zurich, Switzerland
Talk title: Fractal: An open-source framework for reproducible bioimage analysis at scale using OME-Zarrs
Joel Lüthi is a biologist and bioinformatician with a PhD from the University of Zurich, where he studied cardiac differentiation and developed innovative approaches for 3D image analysis in the lab of Prof. Lucas Pelkmans. Following his PhD, he joined the lab of Prof. Prisca Liberali at the Friedrich Miescher Institute to spearhead the development of the Fractal platform, a cutting-edge tool enabling scalable and accessible bioimage analysis using the next generation OME-Zarr file format. In summer 2023, he was appointed Head of Research and Development at the BioVisionCenter at the University of Zurich. In this role, he continues to advance the Fractal platform and drives efforts to make bioimage analysis tools more accessible to researchers globally, empowering new discoveries in life sciences through scalable technology.

Amsterdam University Medical Center, The Netherlands
Talk title: Cellular communities in the tumor microenvironment reflect immune regulation
Dr. F. van Maldegem is assistant professor at Amsterdam University Medical Center, leading the lung cancer tumor microenvironment group at the department of Molecular Cell Biology and Immunology, and affiliated with the Cancer Center Amsterdam and the Amsterdam Institute for Immunology and Infectious diseases. In her research she focusses on the application of multiplex technologies such as Imaging Mass Cytometry to better understand the interactions between the tumor and the immune system. She is leading the EU Horizon SPACETIME project with the aim to improve immunotherapy responses in lung cancer patients.

University of Gothenburg, Sweden
Talk title: Bio-imaging with gas cluster ion beam secondary ion mass spectrometry (GCIB-SIMS)
John studied Chemistry at The University of Manchester Institute of Science and Technology (UMIST) completing his PhD in 2004 under the supervision of John Vickerman. Following research activities at The University of Manchester ranging from atmospheric science to instrument development and bio-imaging applications John moved to Sweden in 2012. John is now Professor of Analytical Chemistry at the University of Gothenburg with research focusing on the development and application of secondary ion mass spectrometry (SIMS) particularly in the life science arena.

University of Manchester, UK
Talk title: Light element, isotopic and trace element mapping in materials science applications with high resolution Secondary Ion Mass Spectrometry (NanoSIMS)
Dr. Katie L. Moore is a Senior Lecturer in Materials Characterisation in the Department of Materials at the University of Manchester. She joined the University of Manchester in October 2014. She graduated with a D.Phil from the University of Oxford in Materials Science in 2011 and has been working in the field of NanoSIMS analysis since 2008. Her research is very diverse but focusses on applications of NanoSIMS analysis in materials science and biology. Specific research interests include hydrogen and deuterium detection with the NanoSIMS to investigate hydrogen pick up, oxidation mechanisms, light element and trace element detection. Katie is also a Royce Institute Research Area Lead for Imaging and Characterisation.

Imperial College London, UK
Talk title: Cryo-Microscopy, Cryo-Sample Preparation and Cryo-Transfer in Materials Science – Applications and Challenges in Complementary Multi-Length Scale Characterisation
James is a Research Facility Manager at the Imperial Centre for Cryo-Microscopy of Materials (I(CM)2) at Imperial College London. The I(CM)2 is a unique facility in the UK for multi-length scale analysis of environmentally sensitive materials. It combines plasma focused ion beam sample preparation with high resolution electron microscopy and atom probe analysis with cryogenic and vacuum transfer between these systems via an inert gas glovebox.
At the I(CM)2, James is responsible for maintaining, providing technical support and training internal and external users in the use of the Local Electrode Atom Probe (LEAP) 5000 XR and developing associated cryogenic and non-cryogenic sample preparation workflows.
James received his B.Sc in Physics at the University of Bath followed by an M.Sc in Nanoscience to Nanotechnology at Swansea University. He then completed his DPhil in Materials at the University of Oxford in the Oxford Atom Probe Group, followed there by a post-doctoral position in the atomic characterisation of irradiated steels for structural nuclear materials and a staff scientist position running the Nuclear Materials Atom Probe (NuMAP) as part of the National Nuclear User Facility.
James is a member of the Steering Committee for the International Field Emission Society, has research interests in technical development in atom probe and focused ion beam and works closely with instrument manufacturers in developing and testing new instrumentation for cryogenic sample preparation and transfer.

University of Edinburgh, UK
Talk title: Mechanisms of biomineral formation in algae
Fabio is Professor of Biomineralization at the School of Chemistry, University of Edinburgh. Fabio obtained his PhD at the Weizmann institute of Science, Israel, and then moved to the Eindhoven University of Technology, The Netherlands as a postdoc before joining the University of Edinburgh as a Chancellor’s Fellow. Fabio’s current research is in biomineralisation, investigating the formation and the structure of mineralized biological materials such as bone and shells. This is an exciting area at the interface between materials sciences, chemistry, crystal growth and biology. Cryo-electron microscopy techniques, including cryoTEM, cryoSEM and cryoFIB-SEM play a central role in Fabio’s research, and in the last years he has also been interested in soft matter, electron crystallography and Ptychographic X-ray tomography as a 3D imaging technique.

University of Warwick, UK
Talk title: Make Mine Milk: using cryo-TEM and cryo-SEM to investigate dairy products
Dr Saskia Bakker is a technical specialist and the Manager of the Advanced Bioimaging RTP at the University of Warwick. In this role she looks after three electron microscopes and their users, and samples ranging from tissue to purified proteins.
Saskia first learned cryo-TEM during her PhD at the University of Leeds, where she was solving the structure of small icosahedral viruses. She then changed direction slightly to cryo-electron tomography, during her post-doc studying human enveloped viruses by at the MRC - University of Glasgow Centre for Virus Research.
Saskia’s current projects include investigating samples from polymer chemistry and extracellular vesicle groups by cryo-TEM and cryo-SEM, as well as tissues and cells by room temperature TEM. She is working closely with microbiologists investigating biofilm structure using cryo-SEM. She is also interested in studying cell entry mechanisms of metallic nanoparticles by array tomography and cryo-X-ray tomography.
Saskia is a member of the Cryo-Microscopy Group organising committee, and the RMS Outreach and Education Committee.

Rosalind Franklin Institute, UK
Title: In-tissue structural biology, cryo-tomography and vEM
Michael completed his D.Phil in structural biology at the University of Oxford, UK, applying in-cell structural biology techniques to investigate the trafficking and egress of viral progeny within cells. After his doctoral studies, he moved to the Max Planck Institute for Molecular Physiology, Germany, as an EMBO Long-Term Fellow. During his fellowship, he established high-throughput FIB-milling and molecular imaging workflows combining them to investigate the structure and architecture of isolated mammalian muscle and human stem-cell-derived cardiomyocytes. Michael’s group is developing novel imaging approaches to unlock new insight into neurobiology and degeneration, particularly focused on disease initiation and progression. They use combinations of light and electron microscopy techniques to reveal high-resolution (ultra) structural information at a tissue level in a robust, high-throughput manner. Their goal is to resolve high-resolution structures inside native tissue on a routine basis, transform our understanding of disease at the molecular, cellular and tissue scale and improve disease diagnosis and treatment. The group’s focus is neurodegenerative disorders such as Alzheimer’s disease, imaging the synaptic organisation within the brain during development and building a molecular atlas of how molecular changes occur across different synaptic types. Molecular observations should unravel new biological and pathological insights. His group works at this interface, demonstrating how new technologies can drive new insight into disease on a molecular scale.

EMPA Swiss Federal Laboratories for Materials Science & Technology, Switzerland
Talk title: MicroCT Imaging for Fibrocartilaginous Tissues
PD Dr. Annapaola Parrilli is a senior scientist and research project leader at the Center for X-ray Analytics at the Swiss Federal Laboratories for Materials Science and Technology (Empa), where she has been working since 2019. She is also a lecturer at the University of Bern and EPFL, specializing in materials science and non-destructive methods. In addition to her research activities, she was Scientific Chair of the Interdisciplinary Panel for PhD and Postdoc Fellowships of the Research Foundation - Flanders (FWO) from 2021 to 2024. She holds a Ph.D. in Biomaterials from the University of Pisa (2015), with a thesis focus on advanced microtomographic techniques for in vitro and in vivo evaluation of biomaterials in orthopedic research. Before joining Empa, she spent ten years as a researcher at the IRCCS Rizzoli Orthopaedic Institute in Bologna, Italy, working at the interface between structural analysis and clinical applications in orthopaedic research.
Her research is highly interdisciplinary, integrating 3D and 4D imaging of biomaterials, organs and tissues with biomechanics, tissue engineering, regenerative medicine and contrast agents for preclinical and translational research. Many of her projects are clinically driven, leveraging her long-standing collaborations with clinicians and clinical settings.

Paul Scherrer Institute PSI, Switzerland
Talk title: Probing the structure and function of the brain with X-rays, electrons and light
Adrian Wanner is an ERCStG-funded Group Leader of Structural Neurobiology at the Paul Scherrer Institute (Switzerland) investigating the molecular, functional and structural profile of neuronal circuits using light, electrons and X-rays. He holds a MSc in Natural Sciences from ETH Zurich with majors in theoretical physics and neuroinformatics, a PhD in neurobiology from FMI and the University of Basel. He was a CV Starr Fellow at Princeton University and founded the biomedical image analysis company ariadne.ai ag.

University of York, UK
Talk title: Quantitative insights from 4D-STEM and ptychographic data analyses
Since 2022, Dr Laura Clark holds a Royal Society University Research Fellowship at the University of York, where she leads the SySTEMatic group - developing 4D-STEM imaging techniques (https://www.york.ac.uk/physics-engineering-technology/people/lauraclark/).
She previously held a Marie Skłodowska-Curie Fellowship at the University of Leeds, following postdoc work in Oxford and Monash (Australia), and obtained her PhD from the EMAT group in Antwerp (Belgium) – these positions encompassed research developing control of the electron beam (designer probes such as vortex beams), and in developing control and analysis of the data (DPC, CoM and ptychography methods).
She is the Vice-Chair of the IOP-EMAG group and sits on the RMS-DAIM committee.

UNIGE, Switzerland
Talk title: Collective cellular dynamics during development: from imaging to theory
Guillaume Salbreux obtained his doctorate in 2008 at the Curie Institute in Paris. He started his research group in 2011, first at the Max Planck Institute in Dresden in Germany then at the Francis Crick Institute in London from 2015. In 2020, he has taken a full professor position at the University of Geneva. His work is oriented at the interface between theoretical physics and biology, and has proposed quantitative and mechanistic explanations of biological processes taking place during embryonic development. His research draws inspiration from the theoretical tools of soft matter and active matter physics to connect the behaviors of biological systems at the molecular, cellular and tissue scales. Guillaume is a theorist who has worked since the start of his career in close collaboration with cell and developmental biologists.

CNR, Italy
Talk title: Inside functional metals: application of EBSD to shape memory alloys and phase change materials
Paola Bassani's scientific activity focuses on metallurgy, particularly on non-ferrous metals. Her research emphasizes the microstructural aspects and the evolution of material properties in relation to production techniques and thermomechanical processing (such as plastic deformation and heat treatments). Her work employs a variety of investigative techniques, including Scanning Electron Microscopy and EBSD, yielding significant results from both scientific and practical perspectives.
Paola has worked with a range of materials, with a particular focus on NiTi-based Shape Memory Alloys. The materials studied were produced using different techniques, including induction melting, Self-Propagating High-Temperature Sintering (SHS), and, more recently, 3D manufacturing via Laser Powder Bed Fusion (LPBF). She also has investigated production processes for obtaining semi-finished products through rolling and/or drawing, and their effects on the functional characteristics of these materials.
In recent years, her research has expanded to the development of new metallic materials, including composite Phase Change Materials (PCMs) for Thermal Energy Storage (TES) and Thermal Energy Management (TEM) applications. This work is currently being explored within the framework of the EIC-Pathfinder project M-TES (www.m-tes.eu).
In addition to her research activities, Paola has contributed to the dissemination of knowledge in metallurgy and microscopy by organizing and lecturing at various courses and events managed by AIM – the Italian Association for Metallurgy. These include four editions of the “SEM Course for Metallurgists” and, in 2022, the first (to the best of the author’s knowledge) informative event in Italy dedicated to the industrial application of EBSD in metallurgy.

University of Leeds, UK
Talk title: Pushing the limits of Electron Backscatter Diffraction (EBSD) analysis to decipher past and present geological processes
Sandra Piazolo is Professor of Structural Geology and Tectonics at the University of Leeds. She was awarded a Marie Curie Fellowship where she applied ‘Quantification of Microstructures applying EBSD and in-situ experiments on rocks and metals: Focus on deformation mechanisms and annealing microstructures’ at the University of Liverpool. In 2004 she moved to become Senior Lecturer to Professor Structural Geology and Tectonics, SU, in Sweden in the establishment of Microdynamic Laboratory – Experiments, Nature and Numerical modelling. In 2010 she moved to the Department of Earth and Planetary Sciences, Macquarie University, Australia where she used EBSD, TKD, Atomprobe Tomography combined with numerical simulations to understand deformation and reaction processes at a fundamental level. Sandra returned to the UK in 2017 continuing to work on a large variety of materials ranging from ice, meteorites, fault zones that have undergone seismic shaking, diamonds and minerals of high relevant to the energy transition.

CEA, France
Talk title: Enabling Complex EBSD Analysis: Integrating Neural Network-Based Simulation with Efficient Dictionary Methods.
Dr Lafond Clément is a physicist and material scientist with expertise at the interaction of physics, microscopy and data science. During a Phd at the Mateis Laboratory (Lyon, France), he developed the eCHORD approach—an innovative alternative to conventional EBSD—for determining crystalline orientation using SEM.
Following the PhD, Clément Lafond joined Carnegie Mellon University (Pittsburgh, USA) as a postdoctoral researcher. There, the focus shifted to combining machine learning with EBSD, aiming to enhance the efficiency and accuracy of microstructural analysis.
Currently at French Alternative Energies and Atomic Energy Commission (CEA) in France, he applies this background to developing EBSD data post-treatment and indexation methods, with a particular focus on metallurgical applications.

University of Illinois at Urbana-Champaign, USA
Talk title: Learning Metal Microstructural Heterogeneity through Spatial Mapping of Diffraction Latent Space Features
I am an assistant professor in Materials Science and Engineering at UIUC. I hold a Ph.D. in Solid Mechanics, Materials Science, and Mechanical Engineering. In 2012, I joined the research group of T.M. Pollock at the University of California Santa Barbara (UCSB), where I became a Specialist in 2015. I received the Hetényi Award in 2018 and 2024, which is given annually for the best research paper published in Experimental Mechanics. I have also been recognized for my contribution to understanding the fatigue properties of metals and was awarded the Superalloy2018 Best Paper Award. In 2024, I received the NSF Career Award and the Kent D. Peaslee Faculty Award. My research interests include metallic materials' mechanical and environmental performance for high temperature, energy, space, and environmental applications. I also focus on high-throughput and advanced data analysis-based characterization methods to accelerate material discovery.

University of Southampton, UK
Talk title: in vivo imaging
Dr Katie Dexter is an in vivo imaging specialist working in the Biomedical Imaging Unit at the University of Southampton. Her work primarily focusses on microCT and optical (fluorescence/bioluminescence) imaging in small animals such as mice, rats, and rabbits. She works on a wide range of medical research projects including fracture healing, cancer, and dementia.
Katie began her career studying physics at the University of Leicester. Throughout her undergraduate studies, she worked on various clinical imaging technologies such as shear wave elastography (ultrasound) for stroke research, hyperspectral imaging for sepsis diagnostics, and a miniature gamma-camera for use in surgery. In her postgraduate research, she produced magnetic nanoparticles intended for use in hyperthermia treatments of cancer.
Katie has worked on several different preclinical imaging systems, including X-ray CT, optical imaging (bioluminescence and fluorescence), nuclear medicine (PET and SPECT), MRI, and ultrasound. She thoroughly enjoys the complexity of imaging animals and producing high quality imaging and analysis protocols for medical research. This weighing up of data quality and animal welfare requires careful consideration and a deep understanding of both the scientific objectives and the ethical responsibilities involved.
Aside from her academic accomplishments, Katie adores outreach. She invites you to try out her CT chocolate quiz!

University of Liverpool, UK
Talk title: X-CT of Structures in the Eye in Health and Disease
Rachel Williams is a professor of ophthalmic bioengineering at The University of Liverpool with over 30 years of experience in the design and development of advanced materials for medical applications. Her expertise lies particularly in the design and characterisation of the bulk and surface properties of materials and how to modify them to optimise the properties for a specific application. She graduated with a BSc in Engineering Science from the University of Exeter and was awarded a scholarship to study at the University of California for a Masters in Biomedical Engineering at the Davis campus. She returned to the UK and joined the Biomaterials group at the University of Liverpool to study for her PhD. She has developed her academic career at The University of Liverpool and about 25 years ago began to specialise in leading research on strategies to develop innovative ways to modify materials and their surfaces to treat sight threatening conditions such as age-related macular degeneration, retinal detachment and surface ocular disorders. She works closely with both clinical and industrial partners to ensure the appropriate translation of her research. From 2014-2020 she held a Fellowship from the EPSRC on Building Advanced Materials to Treat Vision Loss and in the same year received an EPSRC RISE award (Recognising Inspirational Scientists and Engineers).

Diamond Light Source, UK
Talk title: High throughput ptychographic tomography
Darren has been developing and implementing ptychographic imaging methods across the visible, x-ray, and electron regimes since his PhD project on “Ptychographic imaging of mixed states” in 2014. His work on the principle of information multiplexing for broadband radiation and the generalisation of the ptychographic sampling condition has expanded the applicability of the method to new sources and instrumentation. He led the first demonstration of X-ray ptychography with a lab-scale X-ray source, which unlocks the potential of the method for use in laboratories and communities across the world. He now holds the position of Principal Beamline Scientist at the Diamond Light Source, where his implementations of high frame rate ptychography are producing orders of magnitude increases in throughput. By combining X-ray ptychography with hyperspectral detectors, he is also pushing the limits of what is possible with broadband radiation, utilising the full potential from any given source in order to extract the maximum possible information.

MAX IV Laboratory Lund University, Sweden
Talk title: Next Frontiers of Crystal Microscopy
Dina Carbone is Beamline Scientist and Group Manager in the Science Division of MAX IV Laboratory in Lund, Sweden, with long-standing expertise in the development of advanced synchrotron radiation methods based on hard (coherent) x-ray nano beams applied to material science. These include, among others, scanning diffraction and inverse microscopy to investigate the correlation between crystal structure and functionality of confined materials. Dina joined MAX IV in 2014, where she has given a fundamental contribution to the construction of the diffraction endstation of NanoMAX and to the implementation of coherent X-ray based techniques. She is co-author of a book on the use of x-ray nanobeams applied to nanoscience.
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