We are proud to announce our final Plenary Speaker, completing a great line-up set for Manchester next year.
Professor Ralf Jungmann of the Max Planck Institute of Biochemistry, is well-known for his work with super resolution on DNA molecules and more specifically, DNA-PAINT.
DNA-PAINT, published in
Nature Methods in 2014, involves creating
strands" by tagging small pieces of DNA with a fluorescent dye. Each of
these imager strands binds transiently to a matching DNA strand that is
attached to a target molecule, which makes the target appear to blink. Such
blinking, when done right, allows researchers to obtain sub-diffraction
resolution single molecule images.
Then later in 2014, Professor Jungmann and his team published a paper in Science, demonstrating not only the ‘self-assembling DNA cages’ they had created, but crucially, how these could be imaged using 3D DNA-PAINT.
His research group at MPI work on developing novel imaging tools for biological and biomedical applications. Professor Jungmann’s group are now working on extending DNA-PAINT to eventually being able to perform highly multiplexed (hundreds of targets), ultra-resolution (<5 nm), and quantitative (integer counting of molecules) imaging of biomolecules (i.e. proteins and nucleic acids) and their interactions.
Working at the forefront of this field, we believe Professor Jungmann will make for a really interesting speaker at mmc2017 in Manchester next July.