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03 - 06 July 2017, Manchester, UK

Professor John Spence FRS will speak at mmc2017

Professor John Spence FRS is the first Plenary Speaker to join the scientific programme for mmc2017. Professor Spence is Richard Snell Professor of Physics at Arizona State University and Director of Science for the National Science Foundation BioXFEL Science and Technology Centre on the application of X-Ray Free-electron lasers to structural biology.

His research focusses on atomic-resolution electron microscopy for imaging atomic processes in solids, defects and bonding in materials, and instrumentation development for new microscopies. His lab’s work, applying X-ray lasers to biology, was listed in Science as one of the top scientific breakthroughs of 2012. Most recently, he has devoted his research to biological applications of femtosecond X-ray diffraction at the Linac Coherent Light Source at Stanford, the world's first hard X-ray laser, where they use X-ray pulses so brief that they terminate before atoms move, to determine the structure of membrane proteins and viruses which are notoriously difficult to crystallize, in their native environment.

The Spence and Weierstall labs at Arizona State University develop sample-delivery devices for structural and dynamic biology at hard X-ray free-electron lasers (XFEL) around the world. In fact, the first such device was developed in their labs. These include the delivery of hydrated streams of membrane proteins nanocrystals, soluble protein nanocrystals, single particles (with one particle, such as a virus, per shot), 2D crystals, and pump-probe facilities for time-resolved nanocrystallography and solution scattering.
Professor Spence's lab has an active program in the development of new data analysis methods and algorithms for snap-shot X-ray diffraction data, protein nanocrystals, single-particles and for solution scattering experiments at XFELs.

We are excited to hear Professor Spence speak at mmc2017 and look forward to welcoming him to Manchester.


Amended from original text on BioXFEL

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