Dr Lucy Collinson joins the excellent line-up of Keynote Speakers set for mmc2017
Dr Collinson is Head of Electron Microscopy at The Francis Crick Institute in London and is well-regarded in the field of 3D CLEM. Her degree and PhD were in Microbiology, followed by a post-doctoral position in Cell Biology using light and electron microscopy to investigate membrane trafficking pathways at University College London. Since completing her post-doc, she has run biological EM facilities, first at UCL and then at the Cancer Research UK London Research Institute, which became part of the new Francis Crick Institute in 2015. The brand new EM Science Technology Platform has now opened in St Pancras, London, designed and built over a period of almost ten years.
Her facility works with more than forty research groups, imaging samples as diverse as proteins, DNA, cells, tissues and model organisms. The facility uses light, electron and X-ray microscopes, and specialises in Correlative Light and EM (CLEM), Integrated Light and EM (ILEM), Serial Block Face SEM (SBF SEM), Focused Ion Beam SEM (FIB SEM), cryo soft X-ray tomography (SXT) and advanced image analysis techniques. In addition, the lab has it’s own microscope prototyping activity, building new systems where commercial systems are not available to answer specific biological questions.
Recent collaborations with Crick scientists and collaborators have imaged a new niche for Mycobacterium tuberculosis in lymphatic endothelial cells, mechanisms of early autophagosome formation during cell starvation, 3D models of the human central nervous system for treating neurodegeneration, the involvement of Rad51 paralogs in DNA damage repair related to breast and ovarian cancer, the role of Cdc42 in immune cell differentiation, the reformation of the nuclear envelope at cell division, infection of human monocyte-derived macrophages by HIV, and entotic cell-in-cell structures commonly observed in tumours.
She has also been involved in various advisory and community activities, including the STFC Life Sciences and Soft Materials Advisory panel, the BioImagingUK organising committee, the Royal Microscopical Society EM section, the EPSRC EM Working Group and the Society for Electron Microscope Technology committee.
We’re really excited to Dr Collinson’s plenary talk in Manchester next year!